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Advances in Cancer Stem Cell Biology

por Springer US
Condición: Nuevo
149,99 €
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Springer US Advances in Cancer Stem Cell Biology
Springer US - Advances in Cancer Stem Cell Biology

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Descripción

In recent years, cancer stem cells have been recognized as important component in carcinogenesis and they seem to form the basis of many (if not all) tumor types. Cancer stem cells or "cancer cell like stem cells" have been isolated from various cancers of different origin (blood, breast, brain, skin, head and neck, thyroid, cervix, lung, retina, colon, pancreas and so on). Cancer stem cells - rare cells with indefinite proliferative potential that drive the formation and growth of tumours- seem to show intriguing relationships with physiological stem cells. Specifically, these cancer cells show significant similarities in the mechanisms that regulate self-renewal of normal stem cells. Moreover, tumour cells might directly arise from normal stem cells. Further, the cellular biology of cancer stem cells show a lot of similarities with normal stem cells.

Detalles de producto

Ilustraciones:
XII, 343 p.
Indice:
Preface.- Cancer Stem cell. A revisitation of “anaplasia” concept.- Stem cells and cancer stem cells- new insights.- Molecular biology of cancer stem cells.- Biomarkers of cancer stem cells.- Cancer stem cell and the microenvironment.- Leukemia stem cells.- Cancer stem cell and the central nervous system.- Cancer stem cells and glioblastoma multiforme. Pathophysiological and clinical aspects.- Breast cancer stem cells.- Colon cancer stem cells.- Liver Tumor-Initiating Cells / Cancer Stem Cells: Past Studies, Current Status and Future Perspectives.- Pancreatic cancer stem cells.- Cancer stem cell and renal carcinoma.- Cancer stem cells. Proteomic approaches for new potential diagnostic and prognostic biomarkers.- Cancer stem cells. An innovative therapeutic approach.- Cancer stem cell and ATP binding cassette. Which role in chemoresistance?.- Stem cell and cancer stem cells. Biological and clinical interrelationships.- Cancer stem cell and antitumor immunity.- Index
Editor:
Scatena, Roberto;Scatena
Mordente, Alvaro;Mordente
Giardina, Bruno;Giardina
Observaciones:
Identifies a molecular phenotype for modified stem cells


Looks into the first challenge of molecular oncology


Gives insight into pathogenetic mechanisms at the basis of cancer stem cells


Includes supplementary material: sn.pub/extras

Tipo de medio:
Tapa blanda
Editorial:
Springer US
Idioma:
Inglés
Edición:
2012
Número de páginas:
343
Resumen:
In recent years, cancer stem cells have been recognized as an important component in carcinogenesis, and they seem to form the basis of many (if not all) tumor types. This volume explores new developments in cancer stem cell biology.

Datos base

Tipo de producto:
Libro de bolsillo
Fecha de aparición:
8 de diciembre de 2014
Dimensiones del paquete:
0.235 x 0.155 x 0.021 m; 0.544 kg
GTIN:
09781493900596
DUIN:
P4FOPV13S36
149,99 €
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